The online yobs began taunting the singer, 24, just minutes after the birth was confirmed on Saturday.
One said Adele’s baby should be killed because it will be “fat and disabled”.
A Twitter user with the name Vanessa Bieber told 4,000 followers: “Aw Adele gave birth to a baby. Is it fat and handicapped lol? Just murder it already lol.”
Other trolls “joked” that singer Adele would have the material for plenty more heartbreaking songs if her aby died or she got post-natal depression.
Some weirdos even threatened to kill her if she chose their favourite baby name for her son.
The hate-filled web users rushed online within minutes of Saturday’s confirmation that Adele and partner Simon Konecki, 38, were the proud parents of a baby boy.
Tweet and sour ... threat to Adele and baby from weird fan of US singer Bruno Mars
When one Twitter user asked what Adele would sing about on her next album, a troll with the name bRoliQ said: “Maybe her baby will die?”
A fan of US singer Bruno Mars said: “I’ll go see her in the UK and kill her. And kill her baby.”
Another female Twitter user said: “I see Adele has given birth to a boy. If she randomly picks my baby name I may have to kill her.”
Dozens more trolls mocked the London pop sensation about her size. Many retweeted the crass comment: “Adele was pregnant? I thought she was fat.”
The most disturbing comments came from celebrity-obsessed Vanessa Bieber — who claims to be a girl aged 12. Previous tweets included racist rants.
Cruel comment ... revolting remarks about baby allegedly come from a 12-year-old girl
Siobhan Freegard of parenting website Netmums, said: “What’s wrong with these people? This deliberate bile is disgusting.”
Adele, who had worldwide hits with Rolling In The Deep and Someone Like You, has not commented on her new baby.
Twitter said: “We don’t comment on individual users.”
X Factor judge Gary Barlow, 41, and Olympic diver Tom Daley, 18, have been targeted by trolls in recent weeks.
Gary was taunted after his daughter was stillborn and Tom was told he “let down” his dead father by missing out on gold.