The Argentine star's girlfriend Veronica Ojeda,33, confirmed that the pregnancy reports are true to an Argentine website.
The 34-year-old beauty told Ciudad.com that she is four months pregnant with their first child.
The couple are thought to have been trying for another baby since Veronica miscarried in January 2010.
Maradona, 51, whose infamous Hand of God goal helped put England out of the 1986 World Cup, had two daughters with ex-wife Claudia Villafane.
The youngest, Giannina, is married to Man City star Sergio Aguero and made Maradona a granddad in February 2009 by giving birth to son Benjamin in Madrid.
The soccer star has never officially recognised Diego Maradona Jr, born to former lover Cristiana Sinagra when he played for Naples, as his son.
An Italian court sided with the model, ruling the child was his and ordered him to pay maintenance.
His fourth child, a girl, was born in 1996, offspring of a relationship with an Argentine woman but little is known about her.